WEKO3
インデックスリンク
アイテム
Effects of mechanical stress on the mRNA expression of S100A4 and cytoskeletal components by periodontal ligament cells
https://tmdu.repo.nii.ac.jp/records/366
https://tmdu.repo.nii.ac.jp/records/36627cbb80e-4d5b-4520-9a4d-0b694a79dde3
名前 / ファイル | ライセンス | アクション |
---|---|---|
03_Duarte (1.0 MB)
|
Copyright © 1999 Tokyo Medical and Dental University (TMDU)
|
Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2017-08-18 | |||||
タイトル | ||||||
タイトル | Effects of mechanical stress on the mRNA expression of S100A4 and cytoskeletal components by periodontal ligament cells | |||||
タイトル | ||||||
タイトル | Effects of mechanical stress on the mRNA expression of S100A4 and cytoskeletal components by periodontal ligament cells | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | PDL cells | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mechanical stress | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | S100A4 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Calcium-binding protein | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cytoskeleton | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | PDL cells | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | mechanical stress | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | S100A4 | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Calcium-binding protein | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | cytoskeleton | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Duarte, Wagner R.
× Duarte, Wagner R.× 高垣, 裕子× 川瀬, 俊夫× 飯村, 忠浩× 大井田, 新一郎× 大谷, 啓一× 竹永, 啓三× 石川, 烈× 春日井, 昇平 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The periodontal ligament (PDL) functions under constant mechanical stress, and PDL cells obviously control PDL functions under such conditions. We have previously found that the mRNA expression of the Ca2+-binding protein S100A4 and β-actin is higher in the PDL from erupted teeth than in the PDL from teeth under eruption. This suggested a role for S100A4 in the response of PDL cells to mechanical stress, possibly by coupling Ca2+ and the cytoskeletal system. In the present study, we investigated the direct effects of cyclical stretching on the mRNA expression of S100A4 and two cytoskeletal components (β-actin and α-tubulin) by PDL cells. In Northern blotting analysis, the expression of S100A4, β-actin, and α-tubulin mRNAs was higher in the PDL from fully erupted and functional bovine teeth than in partially erupted ones. Similarly, when bovine PDL cells were mechanically stimulated by means of the Flexercell Strain Unit, the expression of S100A4,β-actin, and α-tubulin mRNAs increased over the control levels. The results of our present study indicate that S100A4 is involved in the responses of PDL cells to mechanical stress possibly by coupling Ca2+ to the cytoskeletal system in these cells. | |||||
書誌情報 |
Journal of Medical and Dental Sciences en : Journal of Medical and Dental Sciences 巻 46, 号 3, p. 117-122, 発行日 1999-09 |
|||||
出版者 | ||||||
出版者 | 東京医科歯科大学 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2185-9132 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11163862 | |||||
論文ID(NAID) | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | NAID | |||||
関連識別子 | 130005632299 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 12160257 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.11480/jmds.460303 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |