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CEREBRAL EXTRACELLULAR POTASSIUM CONCENTRATION CHANGE AND CEREBRAL IMPEDANCE CHANGE IN SHORT-TERM ISCHEMIA IN GERBIL
https://tmdu.repo.nii.ac.jp/records/538
https://tmdu.repo.nii.ac.jp/records/53829b4c315-94a7-4215-8fab-b8aeafca8b36
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
01_Yamaguchi.pdf (2.3 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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| 公開日 | 2019-09-26 | |||||||||
| タイトル | ||||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 主題 | Cerebral ischemia | |||||||||
| キーワード | ||||||||||
| 主題 | extracellular ion concentration | |||||||||
| キーワード | ||||||||||
| 主題 | cerebral impedance | |||||||||
| 公開日 | ||||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| 著者 |
Takekane, YAMAGUCHI
× Takekane, YAMAGUCHI
× Takekane, YAMAGUCHI
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Extracellular potassium and calcium ion concentration, field potential (Fp), local EEG and cortical impedance were measured continuously in the cortex and hippocampus of the pentobarbital anesthetized gerbils subjected to 5-minute ischemia produced by bilateral carotid occlusion. Extracellular potassium ([K+]e) and extracellular calcium ([Ca++]e) showed a triphasic change during ischemia followed by a biphasic change after recirculation. The EEG became flat within about 20 seconds. There was a sharp increase in the [K+]e and a sharp decrease in the [Ca++]e, which coincided with the sharp increase in the Fp around one and a half minutes. The impedance increased simultaneously with a large amplitude change of EEG. The [Ca++]e continued to decrease for another 1-2 minutes before returning to the normal values after recirculation whereas the [K+]e began to decrease immediately. The extracellular space (ECS) did not change until depolarization. The rise of the [K+]e and [Ca++]e in the pre-depolarization phase was not explained by the shrinkage of the ECS. The possible explanation for the change of the [Ca++]e in ischemia was discussed. | |||||||||
| 書誌情報 |
The bulletin of Tokyo Medical and Dental University 巻 33, 号 1, p. 1-8, 発行日 1986-03 |
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| 出版者 | ||||||||||
| 出版者 | Tokyo Medical and Dental University | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 2435-0761 | |||||||||
| DOI | ||||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | 10.11480/btmd.330101 | |||||||||
