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Methods: One hundred eighty-two samples of effusions were examined. Cell blocks were prepared from residual samples after LBC preparation, and the details about the diagnostic concordance and difference in cytological characteristics were investigated. Cell block immunostaining was performed to predict the histological type and the primary site of the carcinoma in 32 cases. ALK rearrangement and EGFR mutation were also analyzed using the cell block. Results: The diagnostic concordance rate between LBC and cell block was 97.3%. Diagnoses using LBC and cell block were mismatched in five cases. By immunostaining, the histological type was determined in 91.0% of carcinomas, and primary sites were identified in 76.5% of adenocarcinomas. ALK rearrangement was examined in two cases of lung carcinoma and EGFR mutation was examined in four cases of lung carcinoma. Conclusion: A high concordance rate between LBC and cell block in effusion cytology was found. The main cause of the mismatched diagnosis was the small amount of atypical cells in LBC or cell block. We also showed the utility of cell block in immunostaining and DNA analysis.", "subitem_description_type": "Abstract"}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Tokyo Medical and Dental University"}]}, "item_10001_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "10.11480/jmds.670003", "subitem_relation_type_select": "DOI"}}]}, "item_10001_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright ©2020 Tokyo Medical and Dental University (TMDU)"}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2185-9132", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ayana, Horiguchi"}], "nameIdentifiers": [{"nameIdentifier": "5280", 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Application of cell block preparation in effusion cytology: Analysis of mismatched diagnosis and utility of immunostaining
https://tmdu.repo.nii.ac.jp/records/632
https://tmdu.repo.nii.ac.jp/records/6324ba43f24-6cd5-4ee8-9221-2f936cbcf718
名前 / ファイル | ライセンス | アクション |
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03_Horiguchi.pdf (1.2 MB)
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Copyright ©2020 Tokyo Medical and Dental University (TMDU)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-02-26 | |||||
タイトル | ||||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | cell block | |||||
キーワード | ||||||
主題 | liquid-based cytology | |||||
キーワード | ||||||
主題 | pleural effusion | |||||
キーワード | ||||||
主題 | peritoneal effusion | |||||
キーワード | ||||||
主題 | immunohistochemistry | |||||
公開日 | ||||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Ayana, Horiguchi
× Ayana, Horiguchi× Takashi, Umezawa× Miyaka, Umemori× Satoshi, Ito× Sachiko, Tsuchiya× Shinichi, Hirooka× Takako, Kiyokawa× Masahiro, Ikegami× Hiroyuki, Takahashi× Yurie, Soejima× Motoji, Sawabe× Ayana, Horiguchi× Takashi, Umezawa× Miyaka, Umemori× Satoshi, Ito× Sachiko, Tsuchiya× Shinichi, Hirooka× Takako, Kiyokawa× Masahiro, Ikegami× Hiroyuki, Takahashi× Yurie, Soejima× Motoji, Sawabe |
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抄録 | ||||||
書誌情報 |
Journal of Medical and Dental Sciences 巻 67, p. 21-29, 発行日 2020-02 |
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出版者 | ||||||
出版者 | Tokyo Medical and Dental University | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2185-9132 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.11480/jmds.670003 | |||||
権利 | ||||||
権利情報 | Copyright ©2020 Tokyo Medical and Dental University (TMDU) |