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REACTION OF HAPTOGLOBIN WITH ISOLATED HEMOGLOBIN CHAINS
https://tmdu.repo.nii.ac.jp/records/981
https://tmdu.repo.nii.ac.jp/records/9813c8890bd-a8fb-48cc-8add-b86166a86f5e
名前 / ファイル | ライセンス | アクション |
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04_Sugata.pdf (1.6 MB)
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Copyright ©1971 Tokyo Medical and Dental University (TMDU)
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Item type | 学術雑誌論文 / Journal Article_02(1) | |||||
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公開日 | 2021-10-01 | |||||
タイトル | ||||||
言語 | ||||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yasuo, SUGATA
× Yasuo, SUGATA× Yasuo, SUGATA |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Isolated hemoglobin chain, namely α- or β-chain, with sulfhydryl groups masked with p-chloromercuribenzoate, and αβ dimer partly masked with p-chloromercuribenzoate were tested for their reactivity with haptoglobin. The α-chain reacts with haptoglobin but it was excluded from α-chain haptoglobin complex by the successibly added native hemoglobin. The β-chain does not bind with haptoglobin without α-chain, but readily binds in the presence of α-chain to form a sufficiently stable complex. The αβ dimer masked with its reactive sulfhydryl group seems to bind with haptoglobin as does native hemoglobin. These facts seem to be an evidence that haptoglobin reacts with hemoglobin dimer as a unit and suggest that unit dimer for this reaction is α1-β1 dimer rather than α1-β2 dimer. | |||||
書誌情報 |
The bulletin of Tokyo Medical and Dental University 巻 18, 号 2, p. 123-136, 発行日 1971-06 |
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出版者 | ||||||
出版者 | Tokyo Medical and Dental University | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2435-0761 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.11480/btmd.180204 | |||||
権利 | ||||||
権利情報 | Copyright ©1971 Tokyo Medical and Dental University (TMDU) |