{"created":"2023-05-15T09:23:07.600695+00:00","id":264,"links":{},"metadata":{"_buckets":{"deposit":"537d762e-81f8-4cbc-81cf-7713ca3369e1"},"_deposit":{"created_by":11,"id":"264","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"264"},"status":"published"},"_oai":{"id":"oai:tmdu.repo.nii.ac.jp:00000264","sets":["5:41:84"]},"author_link":["2552","2551","2550"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"85","bibliographicPageStart":"79","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"Journal of Medical and Dental Sciences"},{"bibliographic_title":"Journal of medical and dental sciences","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Endochondral bone formation observed at the mandibular condyle is regulated by various growth factors including insulin-like growth factor-I (IGF-I). In this paper, we describe a method for the local administration of IGF-I to the bilateral mandibular articular cavities of 3- and 12-week-old rats, and the effects of IGF-I on endochondral bone formation by histomorphometric techniques. In 3-week-old IGF-I-treated rats, three days after administration, an increase in bone tissue was found in the area of the subchondral cancellous bone layer. In 12-week-old IGF-I-treated rats, three days after administration, an increase in the thickness of the condylar cartilage and a decrease in bone tissue were observed in the area of the subchondral cancellous bone layer. This study revealed that the local administration of IGF-I on mandibular condyle caused different histological changes between growth and maturation periods. These results indicated that the effects of IGF-I on endochondral bone formation in the mandibular condyle were age-dependent.","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東京医科歯科大学"}]},"item_10002_relation_12":{"attribute_name":"論文ID（NAID）","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"110000076021","subitem_relation_type_select":"NAID"}}]},"item_10002_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"12715923","subitem_relation_type_select":"PMID"}}]},"item_10002_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.11480/jmds.500111","subitem_relation_type_select":"DOI"}}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12028964","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2185-9132","subitem_source_identifier_type":"ISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"伊藤, 公一"},{"creatorName":"Itoh, Kouichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2550","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木, 聖一"},{"creatorName":"Suzuki, Shoichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2551","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"黒田, 敬之"},{"creatorName":"Kuroda, Takayuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2552","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-08-15"}],"displaytype":"detail","filename":"11_Itoh.pdf","filesize":[{"value":"108.7 kB"}],"format":"application/pdf","license_note":"Copyright © 2003 Tokyo Medical and Dental University (TMDU) ","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"11_Itoh","url":"https://tmdu.repo.nii.ac.jp/record/264/files/11_Itoh.pdf"},"version_id":"2e26655d-da1c-413d-993e-a5dff65c2dfd"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"insulin-like growth factor-I","subitem_subject_scheme":"Other"},{"subitem_subject":"mandibular condyle","subitem_subject_scheme":"Other"},{"subitem_subject":"endochondral bone formation","subitem_subject_scheme":"Other"},{"subitem_subject":"rat","subitem_subject_scheme":"Other"},{"subitem_subject":"local administration","subitem_subject_scheme":"Other"},{"subitem_subject":"insulin-like growth factor-I","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mandibular condyle","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"endochondral bone formation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"rat","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"local administration","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of local administration of insulin-like growth factor-I on mandibular condylar growth in rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of local administration of insulin-like growth factor-I on mandibular condylar growth in rats"},{"subitem_title":"Effects of local administration of insulin-like growth factor-I on mandibular condylar growth in rats","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"11","path":["84"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-08-15"},"publish_date":"2017-08-15","publish_status":"0","recid":"264","relation_version_is_last":true,"title":["Effects of local administration of insulin-like growth factor-I on mandibular condylar growth in rats"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-05-15T09:45:45.257053+00:00"}