@article{oai:tmdu.repo.nii.ac.jp:00000505,
 author = {Toshiaki, KASHIWADA and Minoru, TAKAGI and Toshiaki, KASHIWADA and Minoru, TAKAGI},
 issue = {4},
 journal = {The bulletin of Tokyo Medical and Dental University},
 month = {Dec},
 note = {There have been many arguments on the irritating mechanisms of the composite resin on the dental pulp. While the direct irritative effect of the resin has been prefered, some authors considered that the marginal microleakage and the resulting bacterial infection play a more important role in inducing the complicating pulp irritation. We developed a new filling technique, called the direct inlay restoration method, which could prevent the marginal leakage associated with the polymerization shrinkage of the adhesive composite resin.
In this study, we tried to apply our method clinically. None of the 440 cases which were filled with the adhesive composite resin and 60 cases out of 64 cases in which the pulps were directly capped with the adhesive composite resin developed any signs and symptoms of pulp irritation . The other 4 cases developed signs of pulp irritation. Two of those 4 cases were pulpectomized due to spontaneous pain and the other 2 cases turned out to be well after re-restoration. With the informed consent of the patients, the direct pulp capping using the adhesive composite resin was experimentally performed on 6 caries-free 3rd molars and the histopathological examination of these capped molars revealed that neither significant degenerative nor inflammatory changes were brought about in the dental pulp.
These clinical and histopathological observations suggest that the dental pulp irritation after resin filling is not induced by the composite resin itself.},
 pages = {45--52},
 volume = {38},
 year = {1991}
}