@article{oai:tmdu.repo.nii.ac.jp:00000059,
 author = {東, 聡伸 and Azuma, Akinobu and 秋葉, 徳寿 and Akiba, Norihisa and 水口, 俊介 and Minakuchi, Shunsuke},
 issue = {1},
 journal = {Journal of medical and dental sciences, Journal of medical and dental sciences},
 month = {Mar},
 note = {Silica coating modifies hydrophobic denture base materials to have a hydrophilic surface. The purpose of this study was to evaluate the effect of silica coating to a denture base material on resistance to Candida albicans ( C. albicans ) adherence. Specimens were prepared by polymerizing an acrylic denture lining material and polished using silicon carbide paper up an abrasive grade of 1000. The specimens of a coated group were treated three times by a silica coating agent using a nonwoven cloth. The surface properties were evaluated by contact angle measurement, scanning electron microscopy (SEM), and energy dispersive X-ray spectroscopy (EDS). A C. albicans adherence assay was performed after 1.5, 6, and 24 h incubation. The mean contact angle of the coated group showed significantly lower than that of the non-coated group (p < 0.05). In the coated group, the surface roughness decreased in SEM images, and Si was continuously detected in EDS analysis. At 24 h incubation time, the colony forming unit of C. albicans on the coated group was significantly reduced compared to the non-coated group (p < 0.05). These results suggest that hydrophilic surface modification by the silica coating reduces C. albicans adherence and could contribute to daily denture care.},
 pages = {1--7},
 volume = {59},
 year = {2012}
}