{"created":"2023-05-15T09:23:42.265910+00:00","id":954,"links":{},"metadata":{"_buckets":{"deposit":"1c0692ca-d26f-492b-aeb3-d5417447ee57"},"_deposit":{"created_by":3,"id":"954","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"954"},"status":"published"},"_oai":{"id":"oai:tmdu.repo.nii.ac.jp:00000954","sets":["132:294:295"]},"author_link":["6802","6803"],"control_number":"954","item_5_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1972-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"82","bibliographicPageStart":"61","bibliographicVolumeNumber":"19","bibliographic_titles":[{"bibliographic_title":"The bulletin of Tokyo Medical and Dental University"}]}]},"item_5_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Recently the relationship between malignant diseases and serum lactic dehydrogenase (SLDH) is being studied with increasing intensity. The purpose of the present study was made to determine the clinical usefulness of SLDH-III activity in the diagnosis of malignant diseases and was made not only to detect the clinical usefulness of SLDH-III activity in the evaluation of the chemotherapeutic effect on cancer but also to detect the clinical value of SLDH III activity during the follow-up period after the removal of the tumor. The present report is based on studies on one hundred and twenty four patients with carcinoma of various origins and twenty-six patients with benign diseases in whom the SLDH activity and isozymes were measured. The following findings were obtained. SLDH activity increased above the normal range in about seventy per cent of ninety-eight malignant diseases. ST.DH-III activity had an intimate correlation with the clinical therapeutic response. During the follow-up period, the SLDH-III activity apparently decreased in three weeks after the removal of the tumor and increased steadily above the normal when the tumor recurred. These changes were named as the U pattern of SLDH-III. The measurement of the SLDH-III activity is considered to be useful in the diagnosis of malignant diseases and has a considerable value in the evaluation of the chemotherapeutic effect on cancer and in the early detection on the recurrence of the tumor.","subitem_description_type":"Abstract"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tokyo Medical and Dental University"}]},"item_5_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.11480/btmd.190105","subitem_relation_type_select":"DOI"}}]},"item_5_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright ©1972 Tokyo Medical and Dental University (TMDU)"}]},"item_5_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2435-0761","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{}]},{"creatorNames":[{}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-09-30"}],"displaytype":"detail","filename":"05_Nakamura.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","license_note":"Copyright ©1972 Tokyo Medical and Dental University (TMDU)","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"05_Nakamura.pdf","url":"https://tmdu.repo.nii.ac.jp/record/954/files/05_Nakamura.pdf"},"version_id":"90dc4501-0649-4a63-a14f-d7babb4f5c33"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"SERUM LACTIC DEHYDROGENASE ISOZYME IN MALIGNANT DISEASES FOR EVALUATION OF TREATMENT","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{}]},"item_type_id":"5","owner":"3","path":["295"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-09-30"},"publish_date":"2021-09-30","publish_status":"0","recid":"954","relation_version_is_last":true,"title":["SERUM LACTIC DEHYDROGENASE ISOZYME IN MALIGNANT DISEASES FOR EVALUATION OF TREATMENT"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-02-09T06:34:40.150922+00:00"}