@article{oai:tmdu.repo.nii.ac.jp:00000969, issue = {4}, journal = {The bulletin of Tokyo Medical and Dental University}, month = {Dec}, note = {The nasopharynx is an interesting organ, however, investigations on the organ has been almost undeveloped, because this area is hidden and inconspicuous. Inflammation of the nasopharynx appears frequently in combination with allergic diseases and rheumatism. In this case, most become cured or better only by the treatment of nasopharyngitis itself. The authors have tried to clear up the mechanism by measuring the plasma 11-OHCS levels using the method of De Moor et al. (1960). The authors measured the plasma 11-OHCS levels before and immediately after the stimulation of the nasopharynx and calculated the increase rate between the two. The rates of 32 of 35 simple nasopharyngitis patients (91%) were increased. Those of 9 of 12 allergic rhinitis cases (75%) were decreased or unchanged. Those of 5 of 6 steroid-treated patients (83%) were decreased or unchanged. When the nasopharynx was not stimulated the plasma 11-OHCS levels were unchanged or decreased a little. The authors have proved that the increase rate is almost in proportion to the degree of the inflammation except in the allergic rhinitis cases and steroid-treated patients, being 30% or less in the mild cases, 20-50% in the moderate cases, and 40% or more in the severe cases. Generally speaking, as the inflammation subsides, the increase in the plasma 11-OHCS levels becomes mild. Because of the fact that the nasopharyngeal stimulation raises the plasma 11-OHCS level, the authors concluded that treatment of nasopharyngitis is an effective therapy for allergic rhinitis and rheumatism. It is also effective for those who require steroid therapy.}, pages = {333--359}, volume = {19}, year = {1972} }