{"created":"2023-05-15T09:23:44.026899+00:00","id":981,"links":{},"metadata":{"_buckets":{"deposit":"8f2fbdd0-fdcc-419c-ae3e-1acbcc7fd4e5"},"_deposit":{"created_by":3,"id":"981","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"981"},"status":"published"},"_oai":{"id":"oai:tmdu.repo.nii.ac.jp:00000981","sets":["132:299:302"]},"author_link":["6938","6939"],"control_number":"981","item_5_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1971-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"136","bibliographicPageStart":"123","bibliographicVolumeNumber":"18","bibliographic_titles":[{"bibliographic_title":"The bulletin of Tokyo Medical and Dental University"}]}]},"item_5_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Isolated hemoglobin chain, namely α- or β-chain, with sulfhydryl groups masked with p-chloromercuribenzoate, and αβ dimer partly masked with p-chloromercuribenzoate were tested for their reactivity with haptoglobin. The α-chain reacts with haptoglobin but it was excluded from α-chain haptoglobin complex by the successibly added native hemoglobin. The β-chain does not bind with haptoglobin without α-chain, but readily binds in the presence of α-chain to form a sufficiently stable complex. The αβ dimer masked with its reactive sulfhydryl group seems to bind with haptoglobin as does native hemoglobin. These facts seem to be an evidence that haptoglobin reacts with hemoglobin dimer as a unit and suggest that unit dimer for this reaction is α1-β1 dimer rather than α1-β2 dimer.","subitem_description_type":"Abstract"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tokyo Medical and Dental University"}]},"item_5_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.11480/btmd.180204","subitem_relation_type_select":"DOI"}}]},"item_5_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright ©1971 Tokyo Medical and Dental University (TMDU)"}]},"item_5_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2435-0761","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{}]},{"creatorNames":[{}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-10-01"}],"displaytype":"detail","filename":"04_Sugata.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","license_note":"Copyright ©1971 Tokyo Medical and Dental University (TMDU)","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"04_Sugata.pdf","url":"https://tmdu.repo.nii.ac.jp/record/981/files/04_Sugata.pdf"},"version_id":"af218812-3cdf-4c72-bc19-fffabecd52ee"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"REACTION OF HAPTOGLOBIN WITH ISOLATED HEMOGLOBIN CHAINS","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{}]},"item_type_id":"5","owner":"3","path":["302"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-10-01"},"publish_date":"2021-10-01","publish_status":"0","recid":"981","relation_version_is_last":true,"title":["REACTION OF HAPTOGLOBIN WITH ISOLATED HEMOGLOBIN CHAINS"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-02-09T04:09:49.475052+00:00"}