@article{oai:tmdu.repo.nii.ac.jp:00000987,
 issue = {3},
 journal = {The bulletin of Tokyo Medical and Dental University},
 month = {Sep},
 note = {The influence of intravenous administration of 10% fat emulsion and a 12% amino acid solution on the acid-base equilibrium was observed and the factors considered to influence the acid-base equilibrium were also studied. Intravenous infusion of a 10% fat emulsion produced a slight acidotic response, but there was no significant difference or any clinical meaning to this. By infusing a 10% fat emulsion, the blood acetone bodies did not increase in quantity but the blood free fatty acid (FFA) increased two to four times. The acidotic response stated above is considered to be caused by this FFA increase. Intravenous injection of a 12 % amino acid solution produced a marked shift towards metabolic acidosis. The mean value of the pH decreased by 0.03, the mean value of the base excess by 2.8 mEq/l, and the mean value of Pco2 by 2.0mmHg. This phenomenon is regarded as being due to the physical and chemical nature of the amino acid solution.},
 pages = {189--212},
 volume = {18},
 year = {1971}
}