WEKO3
インデックスリンク
アイテム
{"_buckets": {"deposit": "9b4b1d15-0835-4697-99c2-9d0745ff0e11"}, "_deposit": {"created_by": 11, "id": "203", "owners": [11], "pid": {"revision_id": 0, "type": "depid", "value": "203"}, "status": "published"}, "_oai": {"id": "oai:tmdu.repo.nii.ac.jp:00000203", "sets": ["76"]}, "author_link": ["2005", "2006", "2004", "2007"], "item_10002_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2005-03", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "50", "bibliographicPageStart": "43", "bibliographicVolumeNumber": "52", "bibliographic_titles": [{"bibliographic_title": "Journal of Medical and Dental Sciences"}, {"bibliographic_title": "Journal of medical and dental sciences", "bibliographic_titleLang": "en"}]}]}, "item_10002_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Although the association of two distinct autoimmune diseases, Graves\u0027 disease (GD) and myasthenia gravis (MG), is rare, the relationships of clinical and immunological activities between the two diseases remain unknown. In the present study, we investigated whether there exist any relationships between clinical and immunological activities of GD and MG as well as any common characteristics of their HLA antigens in five patients with concomitant association with GD and MG. The present study clearly showed positive relationships between the clinical activities of GD and MG in all five cases. Except for two cases, one with undetectable acetylcholine receptor antibody and another with few sample number, there were positive relationships between two circulating auto-antibodies against TSH receptor and acetylcholine receptor as well as their immunological and clinical activities in the remaining three cases. Furthermore, the present serological HLA typing study revealed that all five cases had common HLA-DQ3. Therefore, our study clearly demonstrates a reverse \u0027see-saw\u0027 relationship between GD and MG based on their clinical and immunological features, and suggests that HLA-DQ3 may play a potential pathogenic role in the concomitant development of the two diseases.", "subitem_description_type": "Abstract"}]}, "item_10002_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "国立大学法人 東京医科歯科大学"}]}, "item_10002_relation_12": {"attribute_name": "論文ID(NAID)", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "110001065275", "subitem_relation_type_select": "NAID"}}]}, "item_10002_relation_13": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "15868740", "subitem_relation_type_select": "PMID"}}]}, "item_10002_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.11480/jmds.520106", "subitem_relation_type_select": "DOI"}}]}, "item_10002_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA12028964", "subitem_source_identifier_type": "NCID"}]}, "item_10002_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2185-9132", "subitem_source_identifier_type": "ISSN"}]}, "item_10002_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "関口, 芳弘"}, {"creatorName": "Sekiguchi, Yoshihiro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "2004", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "原, 義人"}, {"creatorName": "Hara, Yoshihito", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "2005", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "高橋, 真冬"}, {"creatorName": "Takahashi, Mafuyu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "2006", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "平田, 結喜緒"}, {"creatorName": "Hirata, Yukio", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "2007", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-08-14"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "06_sekiguchi.pdf", "filesize": [{"value": "700.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "Copyright © 2005 Tokyo Medical and Dental University (TMDU) ", "licensetype": "license_free", "mimetype": "application/pdf", "size": 700900.0, "url": {"label": "06_sekiguchi", "url": "https://tmdu.repo.nii.ac.jp/record/203/files/06_sekiguchi.pdf"}, "version_id": "567c4465-df7b-4e0b-b257-47298bf6a623"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "HLA typing", "subitem_subject_scheme": "Other"}, {"subitem_subject": "anti-TSH receptor antibody", "subitem_subject_scheme": "Other"}, {"subitem_subject": "anti-acetylcholine receptor antibody", "subitem_subject_scheme": "Other"}, {"subitem_subject": "HLA typing", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "anti-TSH receptor antibody", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "anti-acetylcholine receptor antibody", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Reverse `See-Saw\u0027 Relationship between Graves\u0027 Disease and Myasthenia Gravis; Clinical and Immunological Studies", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Reverse `See-Saw\u0027 Relationship between Graves\u0027 Disease and Myasthenia Gravis; Clinical and Immunological Studies"}, {"subitem_title": "Reverse `See-Saw\u0027 Relationship between Graves\u0027 Disease and Myasthenia Gravis; Clinical and Immunological Studies", "subitem_title_language": "en"}]}, "item_type_id": "10002", "owner": "11", "path": ["76"], "permalink_uri": "https://tmdu.repo.nii.ac.jp/records/203", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-08-14"}, "publish_date": "2017-08-14", "publish_status": "0", "recid": "203", "relation": {}, "relation_version_is_last": true, "title": ["Reverse `See-Saw\u0027 Relationship between Graves\u0027 Disease and Myasthenia Gravis; Clinical and Immunological Studies"], "weko_shared_id": -1}
Reverse `See-Saw' Relationship between Graves' Disease and Myasthenia Gravis; Clinical and Immunological Studies
https://tmdu.repo.nii.ac.jp/records/203
https://tmdu.repo.nii.ac.jp/records/203374befd6-b40b-4fbe-9c8d-6658a96ef181
名前 / ファイル | ライセンス | アクション |
---|---|---|
06_sekiguchi (700.9 kB)
|
Copyright © 2005 Tokyo Medical and Dental University (TMDU)
|
Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2017-08-14 | |||||
タイトル | ||||||
タイトル | ||||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HLA typing | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | anti-TSH receptor antibody | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | anti-acetylcholine receptor antibody | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | HLA typing | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | anti-TSH receptor antibody | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | anti-acetylcholine receptor antibody | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
関口, 芳弘
× 関口, 芳弘× 原, 義人× 高橋, 真冬× 平田, 結喜緒 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Although the association of two distinct autoimmune diseases, Graves' disease (GD) and myasthenia gravis (MG), is rare, the relationships of clinical and immunological activities between the two diseases remain unknown. In the present study, we investigated whether there exist any relationships between clinical and immunological activities of GD and MG as well as any common characteristics of their HLA antigens in five patients with concomitant association with GD and MG. The present study clearly showed positive relationships between the clinical activities of GD and MG in all five cases. Except for two cases, one with undetectable acetylcholine receptor antibody and another with few sample number, there were positive relationships between two circulating auto-antibodies against TSH receptor and acetylcholine receptor as well as their immunological and clinical activities in the remaining three cases. Furthermore, the present serological HLA typing study revealed that all five cases had common HLA-DQ3. Therefore, our study clearly demonstrates a reverse 'see-saw' relationship between GD and MG based on their clinical and immunological features, and suggests that HLA-DQ3 may play a potential pathogenic role in the concomitant development of the two diseases. | |||||
書誌情報 |
Journal of Medical and Dental Sciences en : Journal of medical and dental sciences 巻 52, 号 1, p. 43-50, 発行日 2005-03 |
|||||
出版者 | ||||||
出版者 | 国立大学法人 東京医科歯科大学 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2185-9132 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12028964 | |||||
論文ID(NAID) | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | NAID | |||||
関連識別子 | 110001065275 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 15868740 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.11480/jmds.520106 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |