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Mechanism underlying the prevention of aneurismal rupture by coil embolization
https://tmdu.repo.nii.ac.jp/records/305
https://tmdu.repo.nii.ac.jp/records/3052e79d1bf-d218-4716-bf59-5a202eb6f23c
名前 / ファイル | ライセンス | アクション |
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05_Ueno (202.0 kB)
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Copyright © 2002 Tokyo Medical and Dental University (TMDU)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2017-08-16 | |||||
タイトル | ||||||
タイトル | Mechanism underlying the prevention of aneurismal rupture by coil embolization | |||||
タイトル | ||||||
タイトル | Mechanism underlying the prevention of aneurismal rupture by coil embolization | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cerebral aneurysm | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Endovascular therapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Guglielmi detachable coil | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Cerebral aneurysm | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Endovascular therapy | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Guglielmi detachable coil | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
上野, 淳司
× 上野, 淳司× 松尾, 崇× 杉山, 健× 桶田, 理喜 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | (Object) Endovascular treatment with Guglielmi detachable coil has been developed as a less invasive treatment for cerebral aneurysm. The aim of this study is to clarify the mechanism of the preventive effect of coil embolization. (Method) Two aneurysm models were employed. One was a T-shaped bifurcation tube with a spherical dome made of glass, which was used for the measurement of pressure and visualization of flow pattern. The other model was a T-shaped glass tube with a spherical elastic silicone dome, which was used for the measurement of aneurismal wall displacement due to pulsation of flow. (Result) 1, Guglielmi detachable coil caused no change in intra-aneurismal fluid pressure. 2, Coil insertion obstructed and slowed intra-aneurismal flow. This flow stagnation in the aneurysm might promote thrombus formation. 3, With increase in numbers of coils anchored at the intra-aneurismal wall, the displacement of the wall was considerably depressed. This suggests that coil insertion decreases the stress on the aneurismal wall. (Conclusion) 1, Coil insertion depresses the pulsatile aneurysm wall movement, and diminishes the stress of the aneurysm wall. 2, Coil insertion obstructs intra-aneurismal flow and facilitates thrombus formation in the aneurysm. These two factors may operate synergistically to prevent aneurysm rupture. | |||||
書誌情報 |
Journal of Medical and Dental Sciences en : Journal of Medical and Dental Sciences 巻 49, 号 4, p. 135-141, 発行日 2002-12 |
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出版者 | ||||||
出版者 | 東京医科歯科大学 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2185-9132 | |||||
論文ID(NAID) | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | NAID | |||||
関連識別子 | 110000032781 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 12641384 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.11480/jmds.490405 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |