WEKO3
インデックスリンク
アイテム
{"_buckets": {"deposit": "cdfc34ed-83dd-4a78-bfbd-7f469992f151"}, "_deposit": {"created_by": 3, "id": "859", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "859"}, "status": "published"}, "_oai": {"id": "oai:tmdu.repo.nii.ac.jp:00000859", "sets": ["274"]}, "author_link": ["6328", "6329"], "control_number": "859", "item_5_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1976-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "226", "bibliographicPageStart": "217", "bibliographicVolumeNumber": "23", "bibliographic_titles": [{"bibliographic_title": "The bulletin of Tokyo Medical and Dental University"}]}]}, "item_5_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The present study was conducted, from the view point of the effects of ozone upon rat, to investigate the toxic effects of 5-hydroxytryptamine (5-HT), the changes in the activity of the lung and serum monoamine oxidase (MAO), which metabolizes 5-HT, and the changes in the 5-HT content of various organs. In the rats exposed previously to ozone, a number of animals died by the intraperitoneal administration of 5-HT, though the control rats without previous exposure to ozone didn’t receive any lethal damage by the administration of the same dose of 5-HT. The mortality of the rats exposed previously to ozone increased as the dose of 5-HT was increased and the susceptibility to 5-HT increased as the ozone concentration became higher, but it decreased as the interval between the end of the exposure and 5-HT administration became longer and the increased susceptibility was detectable for as long as 12 1/2 hours. In the rats exposed to ozone, the activity of the lung and serum MAO was significantly inhibited as compared with the control, and these changes in the activity generally paralleled each other with time. In these rats, the 5-HT content of the lung and spleen was significantly increased, that of the brain was significantly decreased but no significant change in the 5-HT content was noted in the liver and kidney.", "subitem_description_type": "Abstract"}]}, "item_5_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Tokyo Medical and Dental University"}]}, "item_5_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "10.11480/btmd.230403", "subitem_relation_type_select": "DOI"}}]}, "item_5_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright ©1976 Tokyo Medical and Dental University (TMDU)"}]}, "item_5_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2435-0761", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Takahito, SUZUKI"}], "nameIdentifiers": [{"nameIdentifier": "6328", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takahito, SUZUKI", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6329", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2021-09-09"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "03_Suzuki.pdf", "filesize": [{"value": "3.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "Copyright ©1976 Tokyo Medical and Dental University (TMDU)", "licensetype": "license_free", "mimetype": "application/pdf", "size": 3100000.0, "url": {"label": "03_Suzuki.pdf", "url": "https://tmdu.repo.nii.ac.jp/record/859/files/03_Suzuki.pdf"}, "version_id": "60908609-f9ac-49c0-88d6-a033d93b3270"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "STUDIES ON THE ACUTE TOXICITY OF 5-HYDROXYTRYPTAMINE IN THE RATS PRE-EXPOSED TO OZONE", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "STUDIES ON THE ACUTE TOXICITY OF 5-HYDROXYTRYPTAMINE IN THE RATS PRE-EXPOSED TO OZONE", "subitem_title_language": "en"}]}, "item_type_id": "5", "owner": "3", "path": ["274"], "permalink_uri": "https://tmdu.repo.nii.ac.jp/records/859", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2021-09-09"}, "publish_date": "2021-09-09", "publish_status": "0", "recid": "859", "relation": {}, "relation_version_is_last": true, "title": ["STUDIES ON THE ACUTE TOXICITY OF 5-HYDROXYTRYPTAMINE IN THE RATS PRE-EXPOSED TO OZONE"], "weko_shared_id": -1}
STUDIES ON THE ACUTE TOXICITY OF 5-HYDROXYTRYPTAMINE IN THE RATS PRE-EXPOSED TO OZONE
https://tmdu.repo.nii.ac.jp/records/859
https://tmdu.repo.nii.ac.jp/records/859e6bd99d1-6bf6-424f-b685-8a805c48df50
名前 / ファイル | ライセンス | アクション |
---|---|---|
03_Suzuki.pdf (3.1 MB)
|
Copyright ©1976 Tokyo Medical and Dental University (TMDU)
|
Item type | 学術雑誌論文 / Journal Article_02(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2021-09-09 | |||||
タイトル | ||||||
言語 | ||||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Takahito, SUZUKI
× Takahito, SUZUKI× Takahito, SUZUKI |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The present study was conducted, from the view point of the effects of ozone upon rat, to investigate the toxic effects of 5-hydroxytryptamine (5-HT), the changes in the activity of the lung and serum monoamine oxidase (MAO), which metabolizes 5-HT, and the changes in the 5-HT content of various organs. In the rats exposed previously to ozone, a number of animals died by the intraperitoneal administration of 5-HT, though the control rats without previous exposure to ozone didn’t receive any lethal damage by the administration of the same dose of 5-HT. The mortality of the rats exposed previously to ozone increased as the dose of 5-HT was increased and the susceptibility to 5-HT increased as the ozone concentration became higher, but it decreased as the interval between the end of the exposure and 5-HT administration became longer and the increased susceptibility was detectable for as long as 12 1/2 hours. In the rats exposed to ozone, the activity of the lung and serum MAO was significantly inhibited as compared with the control, and these changes in the activity generally paralleled each other with time. In these rats, the 5-HT content of the lung and spleen was significantly increased, that of the brain was significantly decreased but no significant change in the 5-HT content was noted in the liver and kidney. | |||||
書誌情報 |
The bulletin of Tokyo Medical and Dental University 巻 23, 号 4, p. 217-226, 発行日 1976-12 |
|||||
出版者 | ||||||
出版者 | Tokyo Medical and Dental University | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2435-0761 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.11480/btmd.230403 | |||||
権利 | ||||||
権利情報 | Copyright ©1976 Tokyo Medical and Dental University (TMDU) |